|
KMID : 0605619980050020184
|
|
Journal of Korean Society of Biological Psychiatry
1998 Volume.5 No. 2 p.184 ~ p.196
|
|
|
Prefrontal Cortex and Schizophrenia
|
|
1정영철/1Young Chul Chung
2은홍배/2Hong Bae Eun
|
|
|
Abstract
|
|
|
With a rapid development of neuroscience, the theories related to the pathophysiology
of schizophrenia have been changed a lot from a simple hyperdopaminergic one to the
various complicated ones. Among these, the theories regarding prefrontal cortex(PFC)
pathology as a cause of schizophrenia are gaining more recognition as the results of
neuroimaging and neuropsychological tests in schizophrenia consistently report
abnormalities in PFC. Therefore, we first reviewed the unique characteristics of PFC in
anatomy, neurochemistry and neurophysiology to enhance an understanding of those
ones. Secondly, various neurotransmitter, neurodevelopmental and neural network theories
of schizophrenia introduced recently were reviewed in terms of PFC pathology.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|